Patent FR2201333 · Riken Institute, Japan · 2 Independent RCTs · 52 + 60 Participants · GMP · CFR21 · FSSC 22000 · EU Manufactured
Patent FR2201333 · Riken Institute, Japan · 2 Independent RCTs · 52 + 60 Participants · GMP · CFR21 · FSSC 22000 · EU Manufactured
Patent FR2201333 · Riken Institute, Japan · 2 Independent RCTs · 52 + 60 Participants · GMP · CFR21 · FSSC 22000 · EU Manufactured
Patent FR2201333 · Riken Institute, Japan · 2 Independent RCTs · 52 + 60 Participants · GMP · CFR21 · FSSC 22000 · EU Manufactured

Our Formulas

Find your formula.

Every AYABiome® formula is built on the same postbiotic core. Your health goal determines which one you need.

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Bestseller

PB-01™

PURE

The original postbiotic. 550+ bioactive metabolites.

New

WW-01™

Women's Wellness

Postbiotic support designed for women's health.

New

MW-01™

Men's Wellness

Postbiotic support designed for men's health.

New

UT-01™

Ultimate

The complete postbiotic stack for total body health.

New

GR-01™

Gut Restore

Targeted postbiotic support for gut lining repair.

Bestseller PB-01™

PURE

550+ bioactive metabolites delivered directly. No conversion required. No live bacteria to survive digestion.

Explore PURE

90 day money back guarantee · Cancel anytime

Delivery

HYDRA® System

Sublingual lozenge. Dissolves in the mouth for faster uptake than capsules.

Origin

Bhutan-Sourced

Untouched Himalayan turmeric. Riken-registered strain. Patent FR2201333.

Stability

No Refrigeration

Heat-stable postbiotic. Full potency from manufacture to use.

Clinical Outcomes

Oxidative Stress

Measurable reduction in oxidative stress markers. Increased SOD activity. 8-week trials.

Formulated with Expert Guidance

"In twenty years of clinical practice, I've rarely recommended a supplement without reservation. PURE is the exception. The mechanism is sound, the evidence is published, and the formulation is unlike anything else on the market."

Kate Arnold

Nutritionist

"I was sceptical — I've tried everything. Two weeks in, my digestion was calmer than it's been in years. Nothing else changed."

Sarah M. · Verified Purchase

Delivery

HYDRA® System

Sublingual lozenge. Dissolves in the mouth for faster uptake than capsules.

Origin

Bhutan-Sourced

Untouched Himalayan turmeric. Riken-registered strain. Patent FR2201333.

Stability

No Refrigeration

Heat-stable postbiotic. Full potency from manufacture to use.

Clinical Outcomes

Oxidative Stress

Measurable reduction in oxidative stress markers. Increased SOD activity. 8-week trials.

Metal Free

Non-GMO

Vegan

Gluten Free

No Additives

Heat Stable

EU Manufactured

Lab Tested

No Live Bacteria

The Evolution

Postbiotics aren’t new. They’re what gut science has been working towards for over a decade.

A brand new science led category redefining gut health and shaping the future of supplementation. AYA BIOME® delivers the end product of fermentation. 550+ bioactive metabolites your body can use immediately, without conversion.

Gut Science
Probiotics est. 1907
Live bacteria, gut dependent

Live microorganisms that must survive your digestive system before reaching the gut. Fewer than 1% make it through gastric conditions intact.

Prebiotics est. 1995
Dietary fibre that feeds bacteria

Non-digestible fibres that selectively feed beneficial gut bacteria. Entirely dependent on the bacteria being there and alive first.

Postbiotics est. 2021
Fermentation metabolites

Bioactive compounds produced when bacteria ferment substrates. Already in their active form. No conversion by your body required.

550+ Bioactive Compounds

A complex metabolite network including short-chain fatty acids, enzymes, peptides and polyphenols. Each with a specific biological function.

HYDRA® Delivery System

AYA BIOME®'s patented delivery technology ensures metabolites reach their target sites intact and fully bioavailable.

Heat stable · No refrigeration

Unlike live probiotics, postbiotics are stable at room temperature. No cold chain. No degradation. No compromised efficacy.

2 Independent RCTs · 52 Adults

Two randomised controlled trials across 52 and 60 adult participants. Results: 23% butyrate increase, 22% reduction in hs-CRP inflammation marker.

Riken Institute Patent

Patent FR2201333. Developed in collaboration with Riken Institute, Japan, one of the world's leading scientific research institutions.

Clinical Evidence

0

% Reduction in Inflammation

hs-CRP marker · RCT 2021

0

% Increase in Butyrate

Short-chain fatty acids · RCT 2021

0

+ Bioactive Metabolites

Per lozenge · Patent FR2201333

0

Independent RCTs

52 + 60 adult participants

0

% Improvement in Oxidative Stress

SOD activity · RCT 2023

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2004

Discovery Year

Our Origin

The science started in one of the world's most remote places.

In the mountain monasteries of Bhutan, a fermented turmeric preparation was observed to produce health outcomes that challenged conventional understanding of gut biology. The monks had been using it for generations. No one in Western science had looked closely at why it worked.

Researchers at the Riken Institute in Japan identified the active mechanism: a specific fermentation process that produces over 550 bioactive metabolites from turmeric — compounds that modulate inflammation, support the gut barrier, and increase short-chain fatty acid production. That process is now protected under Patent FR2201333.

AYABiome® was built to bring that science to market in its purest form. No shortcuts. No fillers. Every formula built on the same fermented turmeric core — validated by independent clinical trials, manufactured to GMP standard in the EU.

Read our story →
Early Users

What early users are saying.

"I've tried every probiotic on the market. This is the first supplement I've taken where I noticed a difference within the first two weeks."

— Alastair J.

"The science behind this is genuinely different. I looked into the clinical trials before ordering and was impressed. Three months in and I won't be stopping."

— Ola M.

"Simple formula, clear evidence, no nonsense. Exactly what I was looking for after years of over-complicated supplement stacks."

— Lee T.

FAQs

Frequently asked questions.

Everything you need to know about postbiotics and AYABiome®.

Postbiotics are the bioactive compounds produced when probiotic bacteria ferment their substrate. Rather than relying on live bacteria to survive digestion and produce these compounds inside you, AYABiome® delivers them directly — already converted, already bioavailable.

Probiotics are live bacteria that must survive stomach acid to reach the gut. Prebiotics are the fibres that feed them. Postbiotics skip both steps — they are the end product of that process, delivered directly. No live organisms, no conversion required, no dependence on gut condition.

In independent clinical trials, meaningful changes in inflammatory markers and digestive comfort were observed from week four onwards. Outcomes continued to improve through the full 12-week trial period. We recommend consistent daily use for at least eight weeks.

Yes. Every AYABiome® formula contains no fillers, binders, or preservatives and is suitable for daily use in healthy adults. If you are pregnant, breastfeeding, taking prescribed medication, or managing a health condition, consult your healthcare provider before use.

No. Because AYABiome® formulas are postbiotics, they contain no live cultures to protect. They are heat-stable and shelf-stable at room temperature. Store in a cool, dry place away from direct sunlight.

Yes. All AYABiome® formulas are 100% vegan, free from gluten, dairy, and artificial additives.

AYABIOME® Fermented Turmeric is backed by two published randomised controlled trials: 52 adults over 12 weeks and 60 adults over 8 weeks. Both trials are available on request.

PURE is our flagship postbiotic for general health and inflammation. Women's Wellness adds S-Equol and targeted vitamins. Men's Wellness includes PomFermenta® and cardiovascular support. GUT RESTORE targets gut lining repair. Ultimate combines all active ingredients in one formula.

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