Questions, answered.

A postbiotic is a preparation of inanimate microorganisms and their components that confers a health benefit on the host. Unlike probiotics (live bacteria) or prebiotics (fibre that feeds bacteria), postbiotics are already in their final, active form — your body receives the finished metabolites directly, with no gut conversion required.

Standard curcumin supplements are poorly absorbed — inconsistent and highly variable between individuals. AYA BIOME™ undergoes a patented fermentation process (FR2201333) using Lactobacillus acidophilus IL-058, transforming turmeric into 550+ bioactive metabolites. The result is a postbiotic that delivers finished compounds directly, with bioavailability estimated at 10–15× that of unfermented curcumin.

HYDRA™ is the name given to the full complex of 550+ bioactive metabolites produced during AYA BIOME™ fermentation. It represents the totality of what fermentation generates — not a single isolated compound, but a complete metabolite profile delivered in an immediately absorbable form.

PURE has been studied in two independent randomised controlled trials. The first — a 12-week RCT in 52 adults — observed a 22% decrease in systemic inflammation (hs-CRP), a 23% increase in butyrate production, and a 21% increase in SOD antioxidant enzyme activity. The second — an 8-week RCT in 60 adults — observed a 4.9% reduction in body fat and a 14.5% improvement in ALT liver enzyme levels. Food supplements should not be used as a substitute for a varied diet.

The fermentation process and original research were developed at the Riken Institute, Japan — one of the world's leading scientific research organisations. The resulting patent (FR2201333) is held by Relina Ltd., the Bulgarian GMP manufacturer responsible for producing AYA BIOME™.

Yes. Because postbiotics contain no live organisms, they carry none of the risks associated with probiotic supplementation in immunocompromised individuals. The AYA BIOME™ fermentation process uses Lactobacillus acidophilus IL-058, a well-characterised strain with an extensive safety record. AYA BIOME™ PURE has been evaluated in clinical settings with no adverse events reported.

PURE is the foundational AYA BIOME™ formula. It contains one ingredient: AYA BIOME™ Fermented Turmeric Extract at 500mg per daily serving, delivered as 2 × 250mg chewable tablets. No proprietary blends. No fillers. No additives. Just the postbiotic, exactly as studied.

Every AYA BIOME™ formula is built on the AYA BIOME™ postbiotic foundation and extended for a specific health goal. The range includes PURE (PB-01™), Women's Wellness (WW-01™), Men's Wellness (MW-01™), Ultimate Longevity (UT-01™), and Gut Restore (GR-01™). We also offer formulas developed specifically for dogs and cats.

Yes. PURE is fully vegan. It contains no animal-derived ingredients, no gelatin, and no animal-sourced excipients.

PURE is free from the 14 major EU allergens. It contains no gluten, dairy, soy, nuts, or shellfish. If you have a specific allergy concern, please contact us before purchasing.

PURE is well-tolerated alongside most supplements. If you are taking prescription medication — particularly anticoagulants or immunosuppressants — we recommend consulting your healthcare provider before starting any new supplement.

We recommend consulting your GP or midwife before taking any supplement during pregnancy or breastfeeding. This is standard guidance and not specific to PURE.

PURE is manufactured by Relina Ltd. in Bulgaria under full GMP certification (CFR21, FSSC 22000). The manufacturing facility meets EU, US, and international pharmaceutical-grade production standards.

Based on the clinical trial data, measurable changes in biomarkers were observed at 8 and 12 weeks. Many customers report noticing changes in digestive comfort within 2–4 weeks. We recommend committing to at least a 90-day trial for a fair assessment. Food supplements should not be used as a substitute for a varied diet.

No. PURE can be taken at any time — morning, midday, or evening. Consistency matters more than timing. Choose a time that fits your routine and stick with it.

We do not recommend exceeding 500mg (2 tablets) per day. The clinical trials were conducted at this dose. Taking more than the studied amount is not advised.

No. PURE can be taken continuously. Unlike some supplements, there is no evidence that cycling AYA BIOME™ is necessary or beneficial.

Simply continue with your next scheduled dose. Do not double up. Missing an occasional dose will not meaningfully affect your results.

Orders placed before 2pm GMT on working days are dispatched the same day. Orders placed after 2pm or at weekends are dispatched the next working day.

We currently ship within the UK. International shipping is being introduced progressively — sign up to the founder list to be notified when your country is available.

We offer a 30-day satisfaction guarantee. If you are not satisfied with your purchase, contact us within 30 days of delivery and we will arrange a full refund. Opened products are accepted for return under this policy.

Subscription ordering is coming soon. Join the founder list to be notified when subscriptions are available, along with the associated pricing.

PURE is packaged in a recyclable amber glass bottle. We are committed to minimising plastic across all packaging formats.

AYA refers to AYA BIOME™ Fermented Turmeric — the active postbiotic at the heart of every formula. Biome refers to the microbiome — the ecosystem of microorganisms that the science of postbiotics is built on.

Yes. AYA BIOME™ is a UK brand. Our formulas are developed in the UK and manufactured in Bulgaria to EU and US GMP standards.

PURE is heat-stable and requires no refrigeration. Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

Yes. All batches are third-party tested for identity, purity, and potency. Certificates of analysis are available on request — email us at hello@thepostbioticcompany.co.uk.

Email us at hello@thepostbioticcompany.co.uk. We aim to respond within one working day.

Postbiotics are the bioactive compounds produced when probiotic bacteria ferment their substrate. Rather than relying on live bacteria to survive digestion and produce these compounds inside you, PURE delivers them directly — already converted, already bioavailable. The result is a more predictable, more consistent effect than probiotics can offer.

Prebiotics feed bacteria. Probiotics are live bacteria that must survive your digestive system before producing any benefit — most don't. PURE skips both steps. Its 550+ bioactive metabolites are already in the form your cells recognise, with no conversion required and no dependence on gut condition.

In our 12-week RCT, meaningful changes in inflammatory markers and digestive comfort were observed from week four onwards. We recommend consistent daily use for at least eight weeks to assess your response. Food supplements should not be used as a substitute for a varied diet.

PURE contains one ingredient — AYA BIOME™ Fermented Turmeric — with no fillers, binders, or preservatives. It is suitable for daily use in healthy adults. If you are pregnant, breastfeeding, taking prescribed medication, or managing a health condition, consult your healthcare provider before use.

No. Because PURE is a postbiotic — not a probiotic — it contains no live cultures to protect. It is heat-stable and shelf-stable at room temperature. Store in a cool, dry place away from direct sunlight.

PURE is a single-ingredient supplement with no known interactions with common vitamins or minerals. If you take prescription medication, check with your doctor — particularly for blood thinners, as turmeric metabolites may have mild anticoagulant properties at high doses.

PURE's active ingredient, AYA BIOME™ Fermented Turmeric, is backed by two published randomised controlled trials. The first (52 adults, 12 weeks) observed a 22% reduction in hs-CRP and an 18% improvement in digestive comfort. The second (60 adults, 8 weeks) recorded a 4.9% reduction in body fat and significant improvements in liver enzyme markers.

Yes. PURE is 100% vegan. It contains no animal-derived ingredients, no gelatin, no lactose, and no allergens. It is also free from gluten, soy, and artificial additives of any kind.

Postbiotics are the bioactive compounds produced when probiotic bacteria ferment their substrate. Women's Wellness delivers them directly — already converted, already bioavailable. The result is a more predictable, more consistent effect than probiotics can offer.

Most women's supplements rely on unfermented botanicals your gut may or may not convert, chronically underdosed across every ingredient. Women's Wellness delivers 550+ bioactive metabolites pre-converted and immediately absorbed, alongside precisely dosed vitamins — including B12 at 20,000% NRV in methylcobalamin form.

In independent clinical trials of AYA BIOME™ Fermented Turmeric, meaningful changes in inflammatory markers and digestive comfort were observed from week four onwards. We recommend consistent daily use for at least eight weeks to assess your response. Food supplements should not be used as a substitute for a varied diet.

Women's Wellness contains seven ingredients with no fillers, binders, or preservatives. It is suitable for daily use in healthy adults. Note: Women's Wellness contains S-Equol derived from fermented soy. If you have a soy allergy, consult your healthcare provider before use.

No. Women's Wellness contains no live cultures to protect. It is heat-stable and shelf-stable at room temperature. Store in a cool, dry place away from direct sunlight.

If you already take a B12 or vitamin D supplement, be mindful that Women's Wellness contains both at meaningful doses. If you take blood thinners or prescription medication, check with your doctor before use.

Women's Wellness is built around AYA BIOME™ Fermented Turmeric, backed by two published randomised controlled trials. The first (52 adults, 12 weeks) observed a 22% reduction in hs-CRP. The second (60 adults, 8 weeks) recorded a 4.9% reduction in body fat and significant improvements in liver enzyme markers.

Yes. Women's Wellness is 100% vegan. It contains no animal-derived ingredients, no gelatin, no lactose, and no artificial additives. It is free from gluten and artificial colours, flavours, or sweeteners.

Most men's supplements rely on unfermented botanicals that depend on your gut to convert them — a process that is inefficient and highly variable. Men's Wellness is built around a postbiotic core: AYA BIOME™ Fermented Turmeric delivers 550+ bioactive metabolites already in the form your cells recognise, with no conversion required.

Postbiotics are the bioactive compounds produced when probiotic bacteria ferment their substrate. Men's Wellness delivers them directly — already converted, already bioavailable. The result is a more predictable, more consistent effect than probiotics can offer.

In the 12-week RCT of AYA BIOME™ Fermented Turmeric, meaningful changes in inflammatory markers and digestive comfort were observed from week four onwards. We recommend daily use for at least eight weeks to assess your response fully. Food supplements should not be used as a substitute for a varied diet.

Men's Wellness contains active ingredients with no fillers, binders, or preservatives. It is suitable for daily use in healthy adult men. If you are taking prescribed medication — particularly blood thinners or hormonal treatments — consult your healthcare provider before use.

No. Men's Wellness uses postbiotic forms — not live cultures — so it contains nothing that degrades without refrigeration. Store in a cool, dry place away from direct sunlight.

Men's Wellness is generally well-tolerated alongside common vitamins and minerals. If you already supplement with zinc or vitamin D, be mindful of your total daily intake. If you take blood thinners or prescription medication, check with your doctor before use.

The postbiotic core — AYA BIOME™ Fermented Turmeric — is backed by two published randomised controlled trials. The first (52 adults, 12 weeks) observed a 22% reduction in hs-CRP and an 18% improvement in digestive comfort. The second (60 adults, 8 weeks) recorded a 4.9% reduction in body fat and significant improvements in liver enzyme markers.

Yes. Men's Wellness is 100% vegan. It contains no animal-derived ingredients, no gelatin, no lactose, and no allergens. It is free from gluten, soy, and artificial additives of any kind.

Postbiotics are the bioactive compounds produced when probiotic bacteria ferment their substrate. GUT RESTORE delivers them directly — already converted, already bioavailable. The result is a more predictable, more consistent effect than probiotics can offer.

Prebiotics feed bacteria. Probiotics are live bacteria that must survive your digestive system before producing any benefit — most don't. GUT RESTORE skips both steps. Its 550+ bioactive metabolites are already in the form your cells recognise, with no conversion required and no dependence on gut condition.

In our 12-week RCT, meaningful changes in inflammatory markers and digestive comfort were observed from week four onwards. We recommend consistent daily use for at least eight weeks to assess your response. Food supplements should not be used as a substitute for a varied diet.

GUT RESTORE contains four active ingredients — AYA BIOME™ Fermented Turmeric, PomFermenta® Fermented Pomegranate, Saccharomyces boulardii Lysate, and Zinc Carnosine — with no fillers, binders, or preservatives. Suitable for daily use in healthy adults. Consult your healthcare provider if pregnant, breastfeeding, or taking prescribed medication.

No. Because GUT RESTORE uses postbiotic and lysate forms — not live cultures — it contains nothing that degrades without refrigeration. It is heat-stable and shelf-stable at room temperature.

GUT RESTORE is generally well-tolerated alongside common vitamins and minerals. If you already supplement with zinc, be mindful of your total daily zinc intake. If you take blood thinners or prescription medication, check with your doctor before use.

GUT RESTORE's primary active, AYA BIOME™ Fermented Turmeric, is backed by two published randomised controlled trials. The first (52 adults, 12 weeks) observed a 22% reduction in hs-CRP and an 18% improvement in digestive comfort. The second (60 adults, 8 weeks) recorded a 4.9% reduction in body fat and significant improvements in liver enzyme markers.

Yes. GUT RESTORE is 100% vegan. It contains no animal-derived ingredients, no gelatin, no lactose, and no allergens. It is free from gluten, soy, and artificial additives of any kind.

Postbiotics are the bioactive compounds produced when probiotic bacteria ferment their substrate. ULTIMATE delivers them directly — already converted, already bioavailable. The result is a more predictable, more consistent effect than probiotics can offer.

Standard multivitamins provide isolated vitamins and minerals that still need to be processed by the body. ULTIMATE goes further — its fermented ingredients deliver 550+ bioactive metabolites already in the form your cells recognise. No conversion required, no dependence on gut condition, and no synthetic fillers.

In our 12-week RCT, meaningful changes in inflammatory markers and digestive comfort were observed from week four onwards. We recommend consistent daily use for at least eight weeks to assess your response. Food supplements should not be used as a substitute for a varied diet.

ULTIMATE contains active ingredients with no fillers, binders, or preservatives. It is suitable for daily use in healthy adults. If you are pregnant, breastfeeding, taking prescribed medication, or managing a health condition, consult your healthcare provider before use.

No. Because ULTIMATE is a postbiotic formula — not a probiotic — it contains no live cultures to protect. It is heat-stable and shelf-stable at room temperature. Store in a cool, dry place away from direct sunlight.

ULTIMATE contains Vitamin B6 and B12, so check for overlap with any other multivitamins you take. If you take prescription medication or blood thinners, check with your doctor before use.

ULTIMATE's lead ingredient, AYA BIOME™ Fermented Turmeric, is backed by two published randomised controlled trials. The first (52 adults, 12 weeks) observed a 22% reduction in hs-CRP and an 18% improvement in digestive comfort. The second (60 adults, 8 weeks) recorded a 4.9% reduction in body fat and significant improvements in liver enzyme markers.

Yes. ULTIMATE is 100% vegan. It contains no animal-derived ingredients, no gelatin, no lactose, and no allergens. It is free from gluten, soy, and artificial additives of any kind.